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Last updated: 2016/10/16
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KCNQ2 monoclonal antibody, clone S26A-23

  • Catalog # : MAB6655
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant KCNQ2.
  • Immunogen:
  • Recombinant fusion protein corresponding to amino acids 1-59 of human KCNQ2.
  • Host:
  • Mouse
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • Detects ~95KDa.
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Western Blot (1-10 ug/mL)
    Immunohistochemistry (0.1-1.0 ug/mL)
    Immunocytochemistry (0.1-1.0 ug/mL)
    Immunofluorescence (1.0-10 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (50% glycerol, 0.09% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western blot analysis in KCNQ2 transfected CHO and HEK cell, using KCNQ2 monoclonal antibody, clone S26A-23 (Cat # MAB6655).
  • Immunohistochemistry
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescence staining in human hippocampus with KCNQ2 monoclonal antibody, clone S26A-23 (Cat # MAB6655).
  • Immunoprecipitation
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Immunohistochemistry
  • Immunoprecipitation
  • Gene Information
  • Entrez GeneID:
  • 3785
  • Gene Name:
  • KCNQ2
  • Gene Alias:
  • Gene Description:
  • potassium voltage-gated channel, KQT-like subfamily, member 2
  • Gene Summary:
  • The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1). At least five transcript variants encoding five different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • neuroblastoma-specific potassium channel protein,potassium voltage-gated channel KQT-like protein 2
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