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Last updated: 2017/2/26
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COL2A1 monoclonal antibody, clone II-4C11

  • Catalog # : MAB6615
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against native COL2A1.
  • Immunogen:
  • Native purified human COL2A1.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • This antibody reacts specifically with human costal cartilage type II collagen.
  • Form:
  • Liquid
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • Western Blot (2 ug/mL)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-10 ug/mL)
    Immunohistochemistry (Frozen sections) (1-10 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 100 mM sodium phosphate buffer, pH 7.0 (1% protease-free BSA)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Publication Reference
  • Applications
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Frozen sections)
  • ELISA
  • Application Image
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Frozen sections)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 1280
  • Gene Name:
  • COL2A1
  • Gene Alias:
  • ANFH,AOM,COL11A3,MGC131516,SEDC
  • Gene Description:
  • collagen, type II, alpha 1
  • Gene Summary:
  • This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000195063,cartilage collagen,chondrocalcin,collagen II, alpha-1 polypeptide
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