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Last updated: 2017/3/26
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PGR monoclonal antibody, clone SP42

  • Catalog # : MAB6558
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic peptide of PGR.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 412-558 of human PGR.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 116
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgG
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:400)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Tissue culture supernatant in TBS buffer, pH 7.5 (1% BSA, 0.09% sodium azide).
  • Storage Instruction:
  • Store at 4°C. Do not freeze.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) of human breast cancer stained with PGR monoclonal antibody, clone SP42 (Cat # MAB6558).
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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  • Gene Information
  • Entrez GeneID:
  • 5241
  • Gene Name:
  • PGR
  • Gene Alias:
  • NR3C3,PR
  • Gene Description:
  • progesterone receptor
  • Gene Summary:
  • This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform A only, and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform B has not been clearly determined. [provided by RefSeq
  • Other Designations:
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