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Last updated: 2016/12/4
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CAV1 monoclonal antibody, clone SP43

  • Catalog # : MAB6546
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic peptide of CAV1.
  • Immunogen:
  • A synthetic peptide corresponding to C-terminus of human CAV1.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 22
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A/G purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.6 (1% BSA, 0.09% sodium azide).
  • Storage Instruction:
  • Store at 4°C. Do not freeze.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) of human lung stained with CAV1 monoclonal antibody, clone SP43 (Cat # MAB6546).
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 857
  • Gene Name:
  • CAV1
  • Gene Alias:
  • BSCL3,CAV,CGL3,MSTP085,VIP21
  • Gene Description:
  • caveolin 1, caveolae protein, 22kDa
  • Gene Summary:
  • The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by a single transcript from this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000025031,caveolae protein, 22-kD,caveolin 1,caveolin 1 caveolae protein, 22kD,caveolin 1, alpha isoform,caveolin 1, beta isoform,caveolin-1 beta isoform protein,cell growth-inhibiting protein 32
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