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Last updated: 2017/10/15
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PTPRM monoclonal antibody, clone T5-AF1A8

  • Catalog # : MAB6540
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against recombinant PTPRM.
  • Immunogen:
  • Recombinant protein corresponding to human PTPRM.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Ammonium sulfate precipitation
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Western Blot (1:1000)
    Immunoprecipitation (1 ug)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In HEPES, 150 mM NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Immunoblot analysis of cell lysates with PTPRM monoclonal antibody, clone T5-AF1A8 (Cat # MAB6540).
    Lane 1 : Bosc 23 cell lysate.
    Lane 2 : Bosc 23 cell lysate transfected with Myc/His/Tau (1-441 amino acids).
    Lane 3 : Bosc 23 cell lysate transfected with Myc/His/PTPRM (848-1452E amino acids).
    Lane 4 : Bosc 23 cell lysate transfected with GFP-Ub+1.
  • Western Blot
  • Immunoprecipitation
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Western Blot
  • Immunoprecipitation
  • Gene Information
  • Entrez GeneID:
  • 5797
  • Gene Name:
  • PTPRM
  • Gene Alias:
  • MGC166994,PTPRL1,R-PTP-MU,RPTPM,RPTPU,hR-PTPu
  • Gene Description:
  • protein tyrosine phosphatase, receptor type, M
  • Gene Summary:
  • The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, which may be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms. [provided by RefSeq
  • Other Designations:
  • protein tyrosine phosphatase mu,protein tyrosine phosphatase, receptor type, mu polypeptide
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