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Last updated: 2017/1/15
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NF2 monoclonal antibody, clone AF1G4

  • Catalog # : MAB6536
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against recombinant NF2.
  • Immunogen:
  • Recombinant His fusion protein corresponding to human NF2.
  • Host:
  • Mouse
  • Reactivity:
  • Human, Mouse, Rat
  • Form:
  • Liquid
  • Purification:
  • Ammonium sulfate precipitation
  • Isotype:
  • IgG2a, kappa
  • Recommend Usage:
  • Western Blot (1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In HEPES, 150 mM NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Immunoblot analysis of cell lysates with NF2 monoclonal antibody, clone AF1G4 (Cat # MAB6536).
    Lane 1 : HeLa cell lysate.
    Lane 2 : 293T cell lysate.
    Lane 3 : MCF-7 cell lysate.
    Lane 4 : HepG2 cell lysate.
    Lane 5 : MOLT-4 cell lysate.
    Lane 6 : C6 cell lysate.
    Lane 7 : L929 cell lysates.
  • Western Blot
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Western Blot
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 4771
  • Gene Name:
  • NF2
  • Gene Alias:
  • ACN,BANF,SCH
  • Gene Description:
  • neurofibromin 2 (merlin)
  • Gene Summary:
  • This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. This gene product has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport. This gene is expressed at high levels during embryonic development; in adults, significant expression is found in Schwann cells, meningeal cells, lens and nerve. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. Two predominant isoforms and a number of minor isoforms are produced by alternatively spliced transcripts. [provided by RefSeq
  • Other Designations:
  • merlin,moesin-ezrin-radixin like,moesin-ezrin-radizin-like protein,neurofibromin 2,neurofibromin 2 (bilateral acoustic neuroma),schwannomerlin,schwannomin
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