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Last updated: 2016/10/23
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DEFA1 monoclonal antibody, clone B539M

  • Catalog # : MAB6523
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against synthetic peptide of DEFA1.
  • Immunogen:
  • A synthetic peptide (conjugated with Hsp70) corresponding to human DEFA1.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • Reacts with cyclic human alpha defensins 1, 2 and 3 (NP1, NP2 and NP3) and recognizes linear human defensins 1-3 that are part of recombinant proteins.
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 1667
  • Gene Name:
  • DEFA1
  • Gene Alias:
  • DEF1,DEFA2,HNP-1,HP-1,MGC138393,MRS
  • Gene Description:
  • defensin, alpha 1
  • Gene Summary:
  • Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. It differs from defensin, alpha 3 by only one amino acid. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000196017,defensin, alpha 1, myeloid-related sequence,defensin, alpha 2,myeloid-related sequence
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