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Last updated: 2017/10/15
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SMARCA4 monoclonal antibody, clone BRG-01

  • Catalog # : MAB6460
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant SMARCA4.
  • Immunogen:
  • Recombinant GST fusion protein corresponding to C-terminus 242 amino acids of human SMARCA4.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 205
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgG2a
  • Recommend Usage:
  • Western Blot (10 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. Do not freeze.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Immunostaining of SMARCA4 by SMARCA4 monoclonal antibody, clone BRG-01 (Cat # MAB6460).
    A - SMARCA4-negative SW-13 cells were transfected with SMARCA4-expression plasmid and analysed by Western blotting for SMARCA4 expression.
    B - HEK293 cytoplasmic (cyt) and nuclear (nuc) lysates were analysed by Western blotting for SMARCA4 presence.
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 6597
  • Gene Name:
  • SMARCA4
  • Gene Alias:
  • BAF190,BRG1,FLJ39786,SNF2,SNF2-BETA,SNF2L4,SNF2LB,SWI2,hSNF2b
  • Gene Description:
  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
  • Gene Summary:
  • The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • ATP-dependent helicase SMARCA4,BRM/SWI2-related gene 1,SNF2-like 4,SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4,brahma protein-like 1,global transcription activator homologous sequence,homeotic gene regulator,mitotic growth
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