Mouse monoclonal antibody raised against synthetic peptide of HSP90AB1.
A synthetic peptide corresponding to amino acids at N-terminus of human HSP90AB1.
Bovine, Human, Mouse
This antibody recognizes the EEVHHG epitope within the N-terminal part of Hsp90b, an ubiquitously expressed protein with calculated MW of 83.3 KDa, however, migrating as a 90 KDa band under reducing SDS-PAGE conditions.
Immunocytochemistry (1 ug/mL) Western Blot (1 ug/mL) Immunoprecipitation (1 ug/mL) The optimal working dilution should be determined by the end user.
In PBS (0.2% BSA, 0.09% sodium azide)
Store at 4°C. Do not freeze. Aliquot to avoid repeated freezing and thawing.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. There are 2 major cytosolic HSP90 proteins, HSP90AA1 (MIM 140571), an inducible form, and HSP90AB1, a constitutive form. Other HSP90 proteins are found in endoplasmic reticulum (HSP90B1; MIM 191175) and mitochondria (TRAP1; MIM 606219) (Chen et al., 2005 [PubMed 16269234]).[supplied by OMIM
OTTHUMP00000016517,OTTHUMP00000016518,OTTHUMP00000016519,OTTHUMP00000039869,heat shock 90kD protein 1, beta,heat shock 90kDa protein 1, beta,heat shock protein beta