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TNFRSF10C monoclonal antibody, clone TRAIL-R3-02

  • Catalog # : MAB6438
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant TNFRSF10C.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 1-280 of human TNFRSF10C.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 35
  • Reactivity:
  • Human
  • Specificity:
  • This antibody reacts with TRAIL-R3, a 35 KDa GPI-anchored extracellular membrane protein expressed mainly on neutrophils.
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, 300 mM NaCl, pH 7.4
  • Storage Instruction:
  • Store at 4°C. Do not freeze.
    Aliquot to avoid repeated freezing and thawing.
  • Publication Reference
  • Applications
  • Flow Cytometry
  • Application Image
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 8794
  • Gene Name:
  • TNFRSF10C
  • Gene Alias:
  • CD263,DCR1,LIT,MGC149501,MGC149502,TRAILR3,TRID
  • Gene Description:
  • tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
  • Gene Summary:
  • The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL. [provided by RefSeq
  • Other Designations:
  • TNF related TRAIL receptor,TNF related apoptosis-inducing ligand receptor 3,TRAIL receptor 3,antagonist decoy receptor for TRAIL/Apo-2L,decoy receptor 1,decoy without an intracellular domain,lymphocyte inhibitor of TRAIL,tumor necrosis factor receptor sup
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