IFNG monoclonal antibody, clone 23
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant IFNG.
Immunogen
Recombinant protein corresponding to full length human IFNG.
Host
Mouse
Reactivity
Human
Specificity
This antibody recognizes both recombinant and native human IFN-gamma.
Form
Lyophilized
Purification
Protein G affinity purification
Isotype
IgG1, kappa
Recommend Usage
ELISA (The antibody reacts with recombinant IFN-gamma coated plate at 0.1 ng/mL of antibody concentration.)
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from 10 mM PBS, pH 7.0.
Storage Instruction
Store at -20°C.
Aliquot after reconstitution to avoid repeated freezing and thawing.
Double distilled water is recommended to adjust the final concentration to 1.00 mg/mL. -
Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — IFNG
Entrez GeneID
3458Gene Name
IFNG
Gene Alias
IFG, IFI
Gene Description
interferon, gamma
Gene Ontology
HyperlinkGene Summary
Interferon-gamma (IFNG), or type II interferon, is a cytokine critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. Aberrant IFNG expression is associated with a number of autoinflammatory and autoimmune diseases. The importance of IFNG in the immune system stems in part from its ability to inhibit viral replication directly, but most importantly derives from its immunostimulatory and immunomodulatory effects. IFNG is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 (MIM 186940) and CD8 (see MIM 186910) cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops (Schoenborn and Wilson, 2007 [PubMed 17981204]).[supplied by OMIM
Other Designations
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Interactome
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Pathway
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Disease
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