SELE monoclonal antibody, clone 1.2B6
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Mouse monoclonal antibody raised against native SELE.
Immunogen
Native purified from TNF activated human umbilical vein endothelial cells .
Host
Mouse
Reactivity
Human
Specificity
human CD62E/E-selectin.
Form
Liquid
Isotype
IgG1
Recommend Usage
Flow Cytometry (1 ug/106 cells)
The optimal working dilution should be determined by the end user.Storage Buffer
In 100 mM BBS, pH 8.2
Storage Instruction
Store at 4°C.
-
Applications
Western Blot
Immunohistochemistry (Frozen sections)
Immunoprecipitation
Enzyme-linked Immunoabsorbent Assay
Inhibition Assay
Flow Cytometry
-
Gene Info — SELE
Entrez GeneID
6401Gene Name
SELE
Gene Alias
CD62E, ELAM, ELAM1, ESEL, LECAM2
Gene Description
selectin E
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis. [provided by RefSeq
Other Designations
OTTHUMP00000032745|endothelial adhesion molecule 1|leukocyte endothelial cell adhesion molecule 2
-
Interactome
-
Pathway
-
Disease
-
Publication Reference
-
The selectins: vascular adhesion molecules.
Tedder TF, Steeber DA, Chen A, Engel P.
FASEB Journal 1995 Jul; 9(10):866.
Application:Blocking, ELISA, Flow Cyt, IHC, Human, Mouse, HUVECs, Neutrophils, Serum, Vascular endothelium.
-
Circulating adhesion molecules in disease.
Gearing AJ, Newman W.
Immunology Today 1993 Oct; 14(10):506.
Application:ELISA, Human, Endothelial cells, Endothelium, Human blood.
-
The selectins: vascular adhesion molecules.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com