MS4A1 monoclonal antibody, clone B-Ly1 (FITC)
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Specification
Product Description
Mouse monoclonal antibody raised against MS4A1.
Immunogen
Human MS4A1.
Host
Mouse
Reactivity
Human
Specificity
Specificity human CD20
Form
Liquid
Conjugation
FITC
Isotype
IgG1
Recommend Usage
Flow Cytometry (10 ul/106 cells)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Frozen sections)
Flow Cytometry
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Gene Info — MS4A1
Entrez GeneID
931Gene Name
MS4A1
Gene Alias
B1, Bp35, CD20, LEU-16, MGC3969, MS4A2, S7
Gene Description
membrane-spanning 4-domains, subfamily A, member 1
Omim ID
112210Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein. [provided by RefSeq
Other Designations
B-lymphocyte cell-surface antigen B1|CD20 antigen|CD20 receptor
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Interactome
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Pathway
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Disease
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Publication Reference
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CD20: a regulator of cell-cycle progression of B lymphocytes.
Tedder TF, Engel P.
Immunology Today 1994 Sep; 15(9):450.
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Isolation and structure of a cDNA encoding the B1 (CD20) cell-surface antigen of human B lymphocytes.
Tedder TF, Streuli M, Schlossman SF, Saito H.
PNAS 1988 Jan; 85(1):208.
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CD20: a regulator of cell-cycle progression of B lymphocytes.
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