TIMP4 monoclonal antibody, clone SB30c (HRP)
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
TIMP4 monoclonal antibody, clone SB30c was stained on cold methanol fixed human pancreatic carcinoma cells with DAPI and Goat Anti-Mouse Ig, human adsorbed-FITC.
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant TIMP4.
Immunogen
Recombinant protein corresponding to human TIMP4.
Host
Mouse
Reactivity
Human
Specificity
human TIMP-4.
Form
Liquid
Conjugation
HRP
Concentration
Lot specific
Isotype
IgG2a
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS, pH 7.4 (50% glycerol)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
TIMP4 monoclonal antibody, clone SB30c was stained on cold methanol fixed human pancreatic carcinoma cells with DAPI and Goat Anti-Mouse Ig, human adsorbed-FITC.Immunohistochemistry (Frozen sections)
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Gene Info — TIMP4
Entrez GeneID
7079Gene Name
TIMP4
Gene Alias
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Gene Description
TIMP metallopeptidase inhibitor 4
Omim ID
601915Gene Ontology
HyperlinkGene Summary
This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. The secreted, netrin domain-containing protein encoded by this gene is involved in regulation of platelet aggregation and recruitment and may play role in hormonal regulation and endometrial tissue remodeling. [provided by RefSeq
Other Designations
tissue inhibitor of metalloproteinase 4
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Interactome
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Disease
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Publication Reference
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Tissue inhibitor of metalloproteinase-4 instigates apoptosis in transformed cardiac fibroblasts.
Tummalapalli CM, Heath BJ, Tyagi SC.
Journal of Cellular Biochemistry 2001 Jan; 80(4):512.
Application：Func, WB-Ti, Human, Fibroblasts, Hearts, T cells.
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TIMP-4 is regulated by vascular injury in rats.
Dollery CM, McEwan JR, Wang M, Sang QA, Liu YE, Shi YE.
Circulation Research 1999 Mar; 84(5):498.
Application：IHC-P, WB-Ti, Rat, Rat carotid arteries.
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Murine tissue inhibitor of metalloproteinases-4 (Timp-4): cDNA isolation and expression in adult mouse tissues.
Leco KJ, Apte SS, Taniguchi GT, Hawkes SP, Khokha R, Schultz GA, Edwards DR.
FEBS Letters 1997 Jan; 401(2-3):213.
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Tissue inhibitor of metalloproteinase-4 instigates apoptosis in transformed cardiac fibroblasts.
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