Klrb1c monoclonal antibody, clone PK136 (FITC)
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More Files
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Flow Cytometry
Splenocytes from a C57BL/6 mouse were double stained with Klrb1c monoclonal antibody, clone PK136 (PE) (Cat # MAB5777) and Klrb1c monoclonal antibody, clone PK136 (FITC) (Cat # MAB5775). Small lymphocytes were then gated and analyzed by flow cytometry.
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Specification
Product Description
Mouse monoclonal antibody raised against native Klrb1c.
Immunogen
Native purified Klrb1c from CE mouse spleen and bone marrow cells enriched for NK-1+ cells.
Host
Mouse
Reactivity
Mouse
Specificity
Mouse NK1.1 alloantigen, Mr 80-85 KDa (39 KDa under reducing conditions).
Form
Liquid
Conjugation
FITC
Isotype
IgG2a, kappa
Recommend Usage
Flow Cytometry (1 ug/106 cells)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunoprecipitation
Flow Cytometry
Splenocytes from a C57BL/6 mouse were double stained with Klrb1c monoclonal antibody, clone PK136 (PE) (Cat # MAB5777) and Klrb1c monoclonal antibody, clone PK136 (FITC) (Cat # MAB5775). Small lymphocytes were then gated and analyzed by flow cytometry. -
Gene Info — Klrb1c
Entrez GeneID
17059Gene Name
Klrb1c
Gene Alias
AI462337, CD161, Ly-59, Ly55c, Ly59, NK-RP1, NK1.1, NKRP1, NKRP140, Nk-1, Nk-1.2, Nk1, Nk1.2, Nkrp1c
Gene Description
killer cell lectin-like receptor subfamily B member 1C
Gene Ontology
HyperlinkGene Summary
locus C|lymphocyte antigen 59|natural killer cell receptor protein NKR-P1C|natural killer cell receptor-P1|natural killer cell-associated antigen 1
Other Designations
killer cell lectin-like receptor subfamily A member 1C|lymphocyte antigen 55 complex, locus C|lymphocyte antigen 59|natural killer cell receptor protein NKR-P1C|natural killer cell receptor-P1|natural killer cell-associated antigen 1
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Publication Reference
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MHC class I molecules on adenovirus E1A-expressing tumor cells inhibit NK cell killing but not NK cell-mediated tumor rejection.
Routes JM, Ryan JC, Ryan S, Nakamura M.
International Immunology 2001 Oct; 13(10):1301.
Application：Flow Cyt, Func, Mouse, Mouse nature killer cells.
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Cytometric and functional analyses of NK and NKT cell deficiencies in NOD mice.
L D Poulton, M J Smyth, C G Hawke, P Silveira, D Shepherd, O V Naidenko, D I Godfrey, A G Baxter.
International Immunology 2001 Jul; 13(7):887.
Application：Flow Cyt, Mouse, Mouse natural killer cells.
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Natural killer cell proliferation induced by anti-NK1.1 and IL-2.
Reichlin A, Yokoyama WM.
Immunology and Cell Biology 1998 Apr; 76(2):143.
Application：Flow Cyt, Mouse, Mouse natural killer cells.
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MHC class I molecules on adenovirus E1A-expressing tumor cells inhibit NK cell killing but not NK cell-mediated tumor rejection.
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