CGB monoclonal antibody, clone 5H4-E2
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Specification
Product Description
Mouse monoclonal antibody raised against CGB.
Immunogen
Immunized with human CGB, conjugated to various carrier proteins.
Host
Mouse
Reactivity
Human
Specificity
5H4-E2 is specific to the Beta chain of hCG. Since the Beta chain levels rise faster in urine, This antibody will detect hCG in urine as early as 1-3 days after successful (artificial) conception as opposed to alpha or dimer specific antibodies. In hCG producing tumors such as certain chorial, testicular, embyionic and lung carcinomas, theBeta chain is also produced in higher quantaties than the alpha or dimeric chains.
Form
Liquid
Isotype
IgG1
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS (0.05% sodium azide)
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry (Frozen sections)
Enzyme-linked Immunoabsorbent Assay
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Gene Info — CGB
Entrez GeneID
1082Gene Name
CGB
Gene Alias
CGB3, hCGB
Gene Description
chorionic gonadotropin, beta polypeptide
Omim ID
118860Gene Ontology
HyperlinkGene Summary
This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene. [provided by RefSeq
Other Designations
chorionic gonadotropin beta 3 subunit|chorionic gonadotropin beta chain|chorionic gonadotropin beta subunit
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