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Last updated: 2017/6/25
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KRT8 monoclonal antibody, clone SB37b

  • Catalog # : MAB5629
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant KRT8.
  • Immunogen:
  • Recombinant protein corresponding to C-terminus of human KRT8.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • Cytokeratin 8.
  • Form:
  • Liquid
  • Isotype:
  • IgG2a
  • Recommend Usage:
  • Immunohistochemistry (10 ug/mL)
    Western Blot (1-2 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 100 mM BBS, pH 8.2
  • Storage Instruction:
  • Store at 4°C.
  • Applications
  • Western Blot
  • Immunohistochemistry (Frozen sections)
  • Immunofluorescence
  • Immunofluorescence
  • Cell Cytospin of the HCC38 breast carcinoma cell line was incubated with KRT8 monoclonal antibody, clone SB37b (Cat # MAB5629). Positive cells were viewed by fluorescence microscopy.
  • ELISA
  • Application Image
  • Western Blot
  • Immunohistochemistry (Frozen sections)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 3856
  • Gene Name:
  • KRT8
  • Gene Alias:
  • CARD2,CK8,CYK8,K2C8,K8,KO
  • Gene Description:
  • keratin 8
  • Gene Summary:
  • This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. [provided by RefSeq
  • Other Designations:
  • cytokeratin 8,keratin, type II cytoskeletal 8
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