FUT4 monoclonal antibody, clone 28
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Specification
Product Description
Mouse monoclonal antibody raised against native FUT4.
Immunogen
Native purified FUT4 from human monocytes, separated from other peripheral blood leucocytes on fibronectin plates.
Host
Mouse
Reactivity
Human
Specificity
human CD15.
Form
Liquid
Isotype
IgM
Recommend Usage
Flow Cytometry (1 ug/106 cells)
The optimal working dilution should be determined by the end user.Storage Buffer
In 100 mM BBS, pH 8.2
Storage Instruction
Store at 4°C.
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Applications
Immunohistochemistry (Frozen sections)
Immunoprecipitation
Flow Cytometry
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Gene Info — FUT4
Entrez GeneID
2526Gene Name
FUT4
Gene Alias
CD15, ELFT, FCT3A, FUC-TIV, FUTIV
Gene Description
fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
Omim ID
104230Gene Ontology
HyperlinkGene Summary
The product of this gene transfers fucose to N-acetyllactosamine polysaccharides to generate fucosylated carbohydrate structures. It catalyzes the synthesis of the non-sialylated antigen, Lewis x (CD15). [provided by RefSeq
Other Designations
ELAM ligand fucosyltransferase|fucosyltransferase 4|fucosyltransferase IV|galactoside 3-L-fucosyltransferase
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Interactome
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Pathway
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Publication Reference
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Expression of the CD15 differentiation antigen (3-fucosyl-N-acetyl-lactosamine, LeX) on putative neutrophil adhesion molecules CR3 and NCA-160.
Stocks SC, Albrechtsen M, Kerr MA.
The Biochemical Journal 1990 Jun; 268(2):275.
Application:Flow Cyt, IP-WB, Human, Human neutrophils.
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Monoclonal antibodies specific for human monocytes, granulocytes and endothelium.
Hogg N, MacDonald S, Slusarenko M, Beverley PC.
Immunology 1984 Dec; 53(4):753.
Application:Func, IF, IHC, IP, Human, Human monocytes, platelets.
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Expression of the CD15 differentiation antigen (3-fucosyl-N-acetyl-lactosamine, LeX) on putative neutrophil adhesion molecules CR3 and NCA-160.
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