MS4A1 monoclonal antibody, clone B-Ly1
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Specification
Product Description
Mouse monoclonal antibody raised against MS4A1.
Immunogen
Human MS4A1.
Host
Mouse
Reactivity
Human
Specificity
human CD20.
Form
Liquid
Isotype
IgG1
Recommend Usage
Flow Cytometry (1 ug/106 cells)
The optimal working dilution should be determined by the end user.Storage Buffer
In 100 mM BBS, pH 8.2
Storage Instruction
Store at 4°C.
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Applications
Immunoprecipitation
Flow Cytometry
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Gene Info — MS4A1
Entrez GeneID
931Gene Name
MS4A1
Gene Alias
B1, Bp35, CD20, LEU-16, MGC3969, MS4A2, S7
Gene Description
membrane-spanning 4-domains, subfamily A, member 1
Omim ID
112210Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein. [provided by RefSeq
Other Designations
B-lymphocyte cell-surface antigen B1|CD20 antigen|CD20 receptor
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Interactome
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Pathway
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Disease
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Publication Reference
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CD20: a regulator of cell-cycle progression of B lymphocytes.
Tedder TF, Engel P.
Immunology Today 1994 Sep; 15(9):450.
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Isolation and structure of a cDNA encoding the B1 (CD20) cell-surface antigen of human B lymphocytes.
Tedder TF, Streuli M, Schlossman SF, Saito H.
PNAS 1988 Jan; 85(1):208.
Application：IP, Human, Raji cells.
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CD20: a regulator of cell-cycle progression of B lymphocytes.
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