Itga4 monoclonal antibody, clone PS/2
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Specification
Product Description
Rat monoclonal antibody raised against native Itga4.
Immunogen
Native purified Itga4 from P815 mastocytoma cells.
Host
Rat
Reactivity
Mouse
Specificity
CD49d, the alpha4 chain (100 KDa) of the VLA-4 integrin heterodimer (Mr 150-KDa).
Form
Liquid
Isotype
IgG2b
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In 100 mM BBS, pH 8.2
Storage Instruction
Store at 4°C.
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Applications
Immunohistochemistry
Immunoprecipitation
Flow Cytometry
Cells from BALB/c bone marrow were stained with Itga4 monoclonal antibody-FITC, following which lymphocytes were gated and analyzed on a FACScan™ flow cytometer (BDIS, San Jose, CA). -
Gene Info — Itga4
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Publication Reference
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Alpha 4 integrin directs virus-activated CD8+ T cells to sites of infection.
Christensen JP, Andersson EC, Scheynius A, Marker O, Thomsen AR.
Journal of Immunology 1995 May; 154(10):5293.
Application:Flow Cyt, Func, Mouse , Mouse spleen cells.
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Expression of murine VCAM-1 in vitro and in different models of inflammation in vivo: correlation with immigration of monocytes.
Henseleit U, Steinbrink K, Sunderkotter C, Goebeler M, Roth J, Sorg C.
Experimental Dermatology 1994 Dec; 3(6):249.
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Evidence for a role of the integrin VLA-4 in lympho-hemopoiesis.
Miyake K, Weissman IL, Greenberger JS, Kincade PW.
The Journal of Experimental Medicine 1991 Mar; 173(3):599.
Application:Flow Cyt, IP, Mouse, 7OZ/3, B815, BM-2, WEHI231 cells.
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Alpha 4 integrin directs virus-activated CD8+ T cells to sites of infection.
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