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Last updated: 2017/11/19
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SOS1 monoclonal antibody, clone AF3F11

  • Catalog # : MAB5560
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against recombinant SOS1.
  • Immunogen:
  • Recombinant His/ABD fusion protein corresponding to human SOS1.
  • Host:
  • Mouse
  • Reactivity:
  • Human, Mouse, Rat
  • Form:
  • Liquid
  • Purification:
  • Ammonium sulfate precipitation
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • Western Blot (1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In HEPES, 150 mM NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Immunoblot analysis of cell lysates.
    Lane 1 : HeLa.
    Lane 2 : Molt 4.
    Lane 3 : HepG2.
    Lane 4 : NIH/3T3.
    Lane 5 : PC-12.
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 6654
  • Gene Name:
  • SOS1
  • Gene Alias:
  • GF1,GGF1,GINGF,HGF,NS4
  • Gene Description:
  • son of sevenless homolog 1 (Drosophila)
  • Gene Summary:
  • This gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000128306,gingival fibromatosis, hereditary, 1,guanine nucleotide exchange factor,son of sevenless homolog 1
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  • Interactome
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