Mouse monoclonal antibody raised against partial recombinant TRIM5.
Recombinant protein corresponding to human TRIM5.
Western Blot (1:1000-1:5000) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100-1:400) Immunohistochemistry (Frozen sections) (1:200-1:400) The optimal working dilution should be determined by the end user.
Store at -20°C. Aliquot to avoid repeated freezing and thawing.
Immunohistochemical analysis of paraffin-embedded metastatic adenocarcinoma (A) showing cytoplasmic localization, human stomach adenocarcinoma (B) showing cytoplasmic localization, using TRIM5 monoclonal antibody, clone 3B11H2 (Cat # MAB5551). The second antibody HRP was used brfore color development with AEC (A) and DAB (B).
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Its function has not been identified. Five alternatively spliced transcript variants for this gene have been described. However, the full length nature of two of the variants has not been determined. [provided by RefSeq
OTTHUMP00000069811,OTTHUMP00000069812,tripartite motif protein TRIM,tripartite motif protein TRIM5,tripartite motif-containing protein 5 alpha