SCD monoclonal antibody, clone CD.E10
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of SCD expression in 293 cells with SCD monoclonal antibody, clone CD.E10 (Cat # MAB5546).
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Specification
Product Description
Mouse monoclonal antibody raised against full length recombinant SCD.
Immunogen
Recombinant protein corresponding to full length human SCD.
Host
Mouse
Reactivity
Human, Mouse
Form
Liquid
Isotype
IgG2B
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS, pH 7.4 (0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of SCD expression in 293 cells with SCD monoclonal antibody, clone CD.E10 (Cat # MAB5546).Immunohistochemistry
Immunoprecipitation
Enzyme-linked Immunoabsorbent Assay
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Gene Info — SCD
Entrez GeneID
6319Gene Name
SCD
Gene Alias
FADS5, MSTP008, SCD1
Gene Description
stearoyl-CoA desaturase (delta-9-desaturase)
Omim ID
604031Gene Ontology
HyperlinkGene Summary
Stearoyl-CoA desaturase (SCD; EC 1.14.99.5) is an iron-containing enzyme that catalyzes a rate-limiting step in the synthesis of unsaturated fatty acids. The principal product of SCD is oleic acid, which is formed by desaturation of stearic acid. The ratio of stearic acid to oleic acid has been implicated in the regulation of cell growth and differentiation through effects on cell membrane fluidity and signal transduction. Four SCD isoforms, Scd1 through Scd4, have been identified in mouse. In contrast, only 2 SCD isoforms, SCD1 and SCD5 (MIM 608370), have been identified in human. SCD1 shares about 85% amino acid identity with all 4 mouse SCD isoforms, as well as with rat Scd1 and Scd2. In contrast, SCD5 shares limited homology with the rodent SCDs and appears to be unique to primates (Zhang et al. (1999) [PubMed 10229681]; Wang et al., 2005 [PubMed 15907797]).[supplied by OMIM
Other Designations
OTTHUMP00000020279|acyl-CoA desaturase|delta-9-desaturase|fatty acid desaturase|predicted protein of HQ0998|stearoyl-CoA desaturase
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