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Last updated: 2016/10/23
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LCK monoclonal antibody, clone 8E5F9, 4B2C7

  • Catalog # : MAB5528
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant LCK.
  • Immunogen:
  • Recombinant protein corresponding to human LCK.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgG2a
  • Recommend Usage:
  • Western Blot (1:500-1:2000)
    ELISA (1:10000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In ascites
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Publication Reference
  • Applications
  • Western Blot
  • Western Blot
  • Western blot analysis using LCK monoclonal antibody, clone 8E5F9, 4B2C7 (Cat # MAB5528) against truncated LCK recombinant protein (Lane 1) and Jurkat cell lysate (Lane 2).
  • Application Image
  • Gene Information
  • Entrez GeneID:
  • 3932
  • Gene Name:
  • LCK
  • Gene Alias:
  • YT16,p56lck,pp58lck
  • Gene Description:
  • lymphocyte-specific protein tyrosine kinase
  • Gene Summary:
  • This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described. [provided by RefSeq
  • Other Designations:
  • T-lymphocyte specific protein tyrosine kinase p56lck,p56(LSTRA) protein-tyrosine kinase,protein tyrosine kinase,proto-oncogene tyrosine-protein kinase LCK
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