Mouse monoclonal antibody raised against native Itgb3.
Native purified Itgb3 from newborn rat bone cell suspension.
Recognizes the (Mr 110 KDa) common Beta-subunit of the gp IIb/IIIa complex and the vitronectin receptor (VNR). The gp IIb (CD41) antigen and the gp IIIa (CD61) antigen form the cell adhesion complex (gp IIb/IIIa) which is the receptor on platelets for fibrinogen, von Willebrand factor, fibronectin and vitronectin. The CD61 antigen is present on virtually all resting and activated platelets. Also known to be present on endothelial cells, megakaryocytes and some leukemias of myeloid, erythroid and lymphoid origin.
Flow Cytometry (using 1ug to stain 1 x 106 cells) The optimal working dilution should be determined by the end user.
In 10 mM KPO4 buffer, 150 mM NaCl, pH 7.2 (1% BSA, 0.09% sodium azide)
Store in the dark at 4°C. Do not freeze. Avoid prolonged exposure to light. Aliquot to avoid repeated freezing and thawing.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.