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Last updated: 2016/12/4
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VEGFA monoclonal antibody, clone SP28

  • Catalog # : MAB5374
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic peptide of VEGFA.
  • Immunogen:
  • A synthetic peptide corresponding to N-terminus of human VEGFA
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Specificity:
  • Molecular weight: 19-28KDa (reduced)
  • Form:
  • Liquid
  • Isotype:
  • IgG
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (Ready-to-use)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Tissue culture supernatant in TBS buffer, pH 7.5 (1% BSA, 0.09% sodium azide).
  • Storage Instruction:
  • Store at 4°C. Do not freeze.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistology (Formalin/paraffin) staining of human angiosarcoma tissue with VEGFA monoclonal antibody, clone SP28 (Cat # MAB5374).
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 7422
  • Gene Name:
  • VEGFA
  • Gene Alias:
  • MGC70609,VEGF,VEGF-A,VPF
  • Gene Description:
  • vascular endothelial growth factor A
  • Gene Summary:
  • This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms. [provided by RefSeq
  • Other Designations:
  • vascular endothelial growth factor isoform VEGF165,vascular permeability factor
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