Mouse monoclonal antibody raised against native CD81.
Native purified CD81 from a B cell line derived from a Burkitt lymphoma.
22.214.171.124 reacts with human CD81 (TAPA-1), a 24 kD member of the TM4 superfamily of proteins with four transmembrane domains. The monoclonal antibody to CD81 have been shown to have anti-proliverative effects on different lymphoid cell lines, particularly those derived from large cell lymphomas. The monoclonal antibody was clustered at the VI WLDA.
The optimal working dilution should be determined by the end user.
In PBS (0.05% sodium azide)
Store at 4°C.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. [provided by RefSeq
26 kDa cell surface protein TAPA-1,CD81 antigen,CD81 antigen (target of antiproliferative antibody 1),target of antiproliferative antibody 1