FUT4 monoclonal antibody, clone BRA4F1
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Specification
Product Description
Mouse monoclonal antibody raised against native FUT4.
Immunogen
Native purified FUT4 from an erythroid-myeloid leukemia cell line (K562 cell).
Host
Mouse
Reactivity
Human
Specificity
BRA4F1 specifically detects CD15. CD15 contains the pentasaccharide lacto-N-fucopentatose III and is particularly expressed on granulocytes and mature neutrophils and on a wide variety of tumor cells including myeloid leukemia, breast, colorectal, and lung cancer cells. The mAb BRA4F1 was clustered at the IVth International Workshop on Leucocyte Differentiation Antigens.
Form
Liquid
Isotype
IgM
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS (0.05% sodium azide)
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry (Frozen sections)
Enzyme-linked Immunoabsorbent Assay
Flow Cytometry
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Gene Info — FUT4
Entrez GeneID
2526Gene Name
FUT4
Gene Alias
CD15, ELFT, FCT3A, FUC-TIV, FUTIV
Gene Description
fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
Omim ID
104230Gene Ontology
HyperlinkGene Summary
The product of this gene transfers fucose to N-acetyllactosamine polysaccharides to generate fucosylated carbohydrate structures. It catalyzes the synthesis of the non-sialylated antigen, Lewis x (CD15). [provided by RefSeq
Other Designations
ELAM ligand fucosyltransferase|fucosyltransferase 4|fucosyltransferase IV|galactoside 3-L-fucosyltransferase
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Interactome
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