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Last updated: 2017/2/19
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FUT1 monoclonal antibody, clone A70-A/A9

  • Catalog # : MAB5296
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against native FUT1.
  • Immunogen:
  • Native purified FUT1 from neuraminidase treated live cells of the T-47D breast carcinoma cell lines.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • A70-A/A9 recognizes the epitope Fucalpha1-2Galbeta1 and is therefore specific to blood group antigen H detecting H2, LeY and Leb and the mAb has no cross-reactivities with the blood group antigens A, B, Lea and Lex . The specificity of the mAb closely resembles that of mAb M/A 15-5 (Miyake & Hakomori, Biochem. 30, 3328 (1991).
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.05% sodium azide)
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Frozen sections)
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Frozen sections)
  • Gene Information
  • Entrez GeneID:
  • 2523
  • Gene Name:
  • FUT1
  • Gene Alias:
  • H,HH,HSC
  • Gene Description:
  • fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
  • Gene Summary:
  • The protein encoded by this gene is a Golgi stack membrane protein that is involved in the creation of a precursor of the H antigen, which is required for the final step in the soluble A and B antigen synthesis pathway. This gene is one of two encoding the galactoside 2-L-fucosyltransferase enzyme. Mutations in this gene are a cause of the H-Bombay blood group. [provided by RefSeq
  • Other Designations:
  • 2-alpha-L-fucosyltransferase,GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 1,alpha (1,2) fucosyltransferase,blood group H alpha 2-fucosyltransferase,fucosyltransferase 1,fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase),fucosy
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