Mouse monoclonal antibody raised against native FUT1.
Native purified FUT1 from neuraminidase treated live cells of the T-47D breast carcinoma cell lines.
A70-A/A9 recognizes the epitope Fucalpha1-2Galbeta1 and is therefore specific to blood group antigen H detecting H2, LeY and Leb and the mAb has no cross-reactivities with the blood group antigens A, B, Lea and Lex . The specificity of the mAb closely resembles that of mAb M/A 15-5 (Miyake & Hakomori, Biochem. 30, 3328 (1991).
The optimal working dilution should be determined by the end user.
In PBS (0.05% sodium azide)
Store at 4°C.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
The protein encoded by this gene is a Golgi stack membrane protein that is involved in the creation of a precursor of the H antigen, which is required for the final step in the soluble A and B antigen synthesis pathway. This gene is one of two encoding the galactoside 2-L-fucosyltransferase enzyme. Mutations in this gene are a cause of the H-Bombay blood group. [provided by RefSeq
2-alpha-L-fucosyltransferase,GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 1,alpha (1,2) fucosyltransferase,blood group H alpha 2-fucosyltransferase,fucosyltransferase 1,fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase),fucosy