CR2 monoclonal antibody, clone 4C5
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Specification
Product Description
Mouse monoclonal antibody raised against CR2.
Immunogen
Immunized subcutaneously in its footpads with fragments of human tonsil.
Host
Mouse
Reactivity
Human
Specificity
This antibody reacts with the CD21 (140kD) molecule, expressed (moderate) on mature B-cells and (at high density) on follicular dendritic cells (FDC).
Form
Liquid
Isotype
IgG2a
Recommend Usage
Immunohistochemistry (Frozen sections) (1:20-1:50)
Flow Cytometry (1:50)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Frozen sections)
Immunofluorescence
Flow Cytometry
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Gene Info — CR2
Entrez GeneID
1380Gene Name
CR2
Gene Alias
C3DR, CD21, SLEB9
Gene Description
complement component (3d/Epstein Barr virus) receptor 2
Gene Ontology
HyperlinkGene Summary
Complement component receptor-2 (CR2) is the membrane protein on B lymphocytes to which the Epstein-Barr virus (EBV) binds during infection of these cells. See also CR1 (MIM 120620). Yefenof et al. (1976) [PubMed 181330] found complete overlapping of EBV receptors and C3 (MIM 120700) receptors on human B lymphocytes.[supplied by OMIM
Other Designations
OTTHUMP00000034421|OTTHUMP00000034447
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Interactome
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