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Last updated: 2016/12/4
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ITGB1 monoclonal antibody, clone DF7

  • Catalog # : MAB5274
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against native ITGB1.
  • Immunogen:
  • Native purified human ITGB1.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • This antibody reacts with the b1 subunit of the integrin protein family. The monoclonal antibody reacts with an extracellular epitope of the b1 integrin molecule. b1 -Integrins mediate cell-extracellular matrix interactions and share a common b-subunit. Monoclonal antibodies against this b1 -Integrin subunit are applicable in paraffin-embedded and frozen sections, immunoblotting and immunoprecipitation. Numerous studies have shown that b1 -Integrins have a distinct and wide cellular distribution and that there are alterations in malignant cells in their b1-integrin expression. Monoclonal antibody to b1 integrin is derived from the hybridoma produced by fusion between myeloma cells and Balb/c spleen cells.
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Western Blot (1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (1% BSA, 0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • ELISA
  • Application Image
  • Western Blot
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 3688
  • Gene Name:
  • ITGB1
  • Gene Alias:
  • CD29,FNRB,GPIIA,MDF2,MSK12,VLA-BETA,VLAB
  • Gene Description:
  • integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
  • Gene Summary:
  • Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000019420,OTTHUMP00000046253,OTTHUMP00000063731,OTTHUMP00000063732,OTTHUMP00000063733,fibronectin receptor beta subunit,integrin VLA-4 beta subunit,integrin beta 1
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