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Last updated: 2016/10/16
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ITGAE monoclonal antibody, clone LF61

  • Catalog # : MAB5260
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against native ITGAE.
  • Immunogen:
  • Native purified ITGAE from hairy cell leukaemia cells.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • LF61 recognizes the human CD103 cell surface antigen, a glycoprotein expressed by approximately 1% of peripheral blood lymphocytes, activated T lymphocytes and by hairy cell leukaemia cells. The antigen is also expressed by intraepithelial lymphocytes. It has recently been shown to be identical to the alpha E integrin.
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBSd (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Frozen sections)
  • Immunoprecipitation
  • Flow Cytometry
  • Application Image
  • Immunohistochemistry (Frozen sections)
  • Immunoprecipitation
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 3682
  • Gene Name:
  • Gene Alias:
  • CD103,HUMINAE,MGC141996
  • Gene Description:
  • integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
  • Gene Summary:
  • Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation. [provided by RefSeq
  • Other Designations:
  • HML-1 antigen,antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide,integrin alpha-IEL,integrin, alpha E
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