B3GAT1 monoclonal antibody, clone 6-13-19-1
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Specification
Product Description
Mouse monoclonal antibody raised against native B3GAT1.
Immunogen
Native purified B3GAT1 from JURKAT T-cell line.
Host
Mouse
Reactivity
Human
Specificity
This antibody reacts with a 110 kD antigen present on the peripheral blood lymphocyte subset (primarily large granular lymphocytes) identified by the HNK-1 monoclonal antibody. It recognizes part of the Natural Killer cell population. CD57 is furthermore present on cells in neuroectodermal tissue.
Form
Liquid
Isotype
IgM
Recommend Usage
Immunofluorescence (1:5)
The optimal working dilution should be determined by the end user.Storage Buffer
In tissue culture supernatant
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Immunohistochemistry
Immunofluorescence
Microcytotoxicity Test
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Gene Info — B3GAT1
Entrez GeneID
27087Gene Name
B3GAT1
Gene Alias
CD57, GLCATP, GlcAT-P, GlcUAT-P, HNK-1, HNK1, LEU7, NK-1
Gene Description
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)
Omim ID
151290Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the glucuronyltransferase gene family. These enzymes exhibit strict acceptor specificity, recognizing nonreducing terminal sugars and their anomeric linkages. This gene product functions as the key enzyme in a glucuronyl transfer reaction during the biosynthesis of the carbohydrate epitope HNK-1 (human natural killer-1, also known as CD57 and LEU7). Alternate transcriptional splice variants have been characterized. [provided by RefSeq
Other Designations
CD57 antigen|LEU7 antigen|UDP-GlcUA:glycoprotein beta-1,3-glucuronyltransferase|beta-1,3-glucuronyltransferase 1|galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1|glucuronosyltransferase P
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Interactome
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Pathway
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