Mouse monoclonal antibody raised against native ITGB1.
Native purified human ITGB1.
This antibody reacts with the beta1 subunit of the integrin protein family and seems to be human specific. This antibody reacts with an extracellular epitope of the beta1 integrin molecule. beta1 -Integrins mediate cell-extracellular matrix interactions and share a common beta-subunit. Numerous studies have shown that beta1 -Integrins have a distinct and wide cellular distribution and that there are alterations in malignant cells in their beta1-integrin expression.
Western Blot (1:1000) The optimal working dilution should be determined by the end user.
In PBS (1% BSA, 0.09% sodium azide)
Store at 4°C.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. [provided by RefSeq