Mouse monoclonal antibody raised against native CEACAM5.
Native purified CEACAM5 from human granulocytes.
The monoclonal antibody is directed against the CD66e-antigen, a 180-200 kD phosphoprotein, 90 kD PI-linked protein, which is expressed on mature human granulocytes. After activation of the granulocutes, expression the antigen is strongly increased. It reacts with 100% of mature human peripheral granulocytes. The monoclonal antibody reacts weakly with malignant cells of patients with B-cell derived chronic lymphoid leukemia (CLL). The monoclonal antibody does not react with normal human peripheral B-cells, T-cells, monocytes and platelets. In immunohistology This antibody reacts with a subpopulation of tissue macrophages and the Carcino Embryonic Antigen (CEA) expressed on colon carcinoma and other carcinomas.
The optimal working dilution should be determined by the end user.
In 20 mM Tris, 150 mM NaCl, pH 8.0 (10 mg BSA, 0.001% thimerosal)
Store at 4°C.
This product contains thimerosal: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.