CD40LG monoclonal antibody, clone TRAP1.3.6
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Specification
Product Description
Mouse monoclonal antibody raised against native CD40LG.
Immunogen
Native purified CD40LG from mouse myeloma cell line transfected with human CD40LG.
Host
Mouse
Reactivity
Human
Specificity
TRAP1.3.6 recognizes the human CD154 cell surface antigen, a 32kD glycoprotein also known as CD40 ligand. CD154 is expressed on activated T lymphocytes, predominantly CD4 +ve and also on some basophils and mast cells.TRAP1.3.6 binds to CD154 at an epitope distinct from the CD40 binding site.
Form
Liquid
Isotype
IgG1
Recommend Usage
Flow Cytometry (10 ul of the suggested working dilution (1:10-1:50) to label 106 cells in 100 ul)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Flow Cytometry
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Gene Info — CD40LG
Entrez GeneID
959Gene Name
CD40LG
Gene Alias
CD154, CD40L, HIGM1, IGM, IMD3, T-BAM, TNFSF5, TRAP, gp39, hCD40L
Gene Description
CD40 ligand
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome. [provided by RefSeq
Other Designations
CD40 antigen ligand|OTTHUMP00000024130|T-B cell-activating molecule|TNF-related activation protein|tumor necrosis factor (ligand) superfamily member 5
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