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Last updated: 2017/12/10
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IFNGR1 monoclonal antibody, clone BB1E2

  • Catalog # : MAB5222
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant IFNGR1.
  • Immunogen:
  • Recombinant protein corresponding to chimeric protein with amino acids 17-245 of human IFNGR1 and 11 amino acids of the c-myc proto-oncogene.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • In Western Blotting only one protein band is stained corresponding to a MW of 43,000, which is equal to the MW for the glycosylated extracellular part of the human extra-cellular interferon-gamma receptor (fused to c-myc), and a MW of 27,000 corresponding to the non-glycosylated part (fused to c-myc). This antibody does not neutralise biological activity of interferon gamma.
  • Form:
  • Liquid
  • Isotype:
  • IgG2a
  • Recommend Usage:
  • Flow Cytometry (1 ug to label 106 cells in 100 ul)
    Flow Cytometry (1-10 ug/mL)
    ELISA (1 ug/mL)
    Western Blot (1 ug/mL)
    Immunohistochemistry (1-10 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Immunohistochemistry (Frozen sections)
  • ELISA
  • Flow Cytometry
  • Application Image
  • Western Blot
  • Immunohistochemistry (Frozen sections)
  • ELISA
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 3459
  • Gene Name:
  • IFNGR1
  • Gene Alias:
  • CD119,FLJ45734,IFNGR
  • Gene Description:
  • interferon gamma receptor 1
  • Gene Summary:
  • This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection. [provided by RefSeq
  • Other Designations:
  • AVP, type 2,CD119 antigen,OTTHUMP00000017285,antiviral protein, type 2,immune interferon receptor 1,interferon-gamma receptor alpha chain
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