Product Browser

Last updated: 2017/9/24
  • Related Product Showcase

Product Compare

Product Compare Cancel Click this icon to add products to compare list. Select up to 10 products.

Quick Order (Tutorial)

Input Catalog #,
place order here!
Catalog # :
  • Where to buy
  • Choose your location

CD1 monoclonal antibody, clone RIV12

  • Catalog # : MAB5204
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against native CD1.
  • Immunogen:
  • Native purified CD1 from human peripheral lymphocytes.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • RIV12, selected by ELISA, cytotoxicity tests and FACS analysis appeared to be an /CD1 reacting with a 49 KDa molecule on human thymocytes. Splenocytes of the mouse were fused with mouse myeloma cells of the 653 cell line.
  • Form:
  • Liquid
  • Isotype:
  • IgG
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.05% sodium azide)
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Frozen sections)
  • ELISA
  • Flow Cytometry
  • Application Image
  • Immunohistochemistry (Frozen sections)
  • ELISA
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 909
  • Gene Name:
  • CD1A
  • Gene Alias:
  • CD1,FCB6,HTA1,R4,T6
  • Gene Description:
  • CD1a molecule
  • Gene Summary:
  • This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternatively spliced transcript variants have been observed, but their biological validity has not been determined. [provided by RefSeq
  • Other Designations:
  • CD1A antigen,CD1A antigen, a polypeptide,OTTHUMP00000018907,T-cell surface antigen T6/Leu-6,T-cell surface glycoprotein CD1a,cluster of differentiation 1 A,cortical thymocyte antigen CD1A,differentiation antigen CD1-alpha-3,epidermal dendritic cell marker
  • Gene Information
  • Entrez GeneID:
  • 910
  • Gene Name:
  • CD1B
  • Gene Alias:
  • CD1,CD1A,MGC125990,MGC125991,R1
  • Gene Description:
  • CD1b molecule
  • Gene Summary:
  • This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens. [provided by RefSeq
  • Other Designations:
  • CD1B antigen,CD1B antigen, b polypeptide,OTTHUMP00000018908,T-cell surface glycoprotein CD1b,cortical thymocyte antigen CD1B,differentiation antigen CD1-alpha-3
  • Gene Information
  • Entrez GeneID:
  • 911
  • Gene Name:
  • CD1C
  • Gene Alias:
  • BDCA1,CD1,CD1A,R7
  • Gene Description:
  • CD1c molecule
  • Gene Summary:
  • This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known. [provided by RefSeq
  • Other Designations:
  • CD1C antigen,CD1C antigen, c polypeptide,OTTHUMP00000018909,T-cell surface glycoprotein CD1c,cortical thymocyte antigen CD1C,differentiation antigen CD1-alpha-3
  • Gene Information
  • Entrez GeneID:
  • 912
  • Gene Name:
  • CD1D
  • Gene Alias:
  • CD1A,MGC34622,R3
  • Gene Description:
  • CD1d molecule
  • Gene Summary:
  • This gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail. [provided by RefSeq
  • Other Designations:
  • CD1D antigen,CD1D antigen, d polypeptide,HMC class I antigen-like glycoprotein CD1D,OTTHUMP00000024053,T-cell surface glycoprotein CD1d,differentiation antigen CD1-alpha-3,thymocyte antigen CD1D
  • Gene Information
  • Entrez GeneID:
  • 913
  • Gene Name:
  • CD1E
  • Gene Alias:
  • CD1A,R2
  • Gene Description:
  • CD1e molecule
  • Gene Summary:
  • This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes within Golgi compartments, endosomes, and lysosomes, and is cleaved into a stable soluble form. The soluble form is required for the intracellular processing of some glycolipids into a form that can be presented by other CD1 family members. Several alternatively spliced transcript variants encoding different isoforms have been described. Additional transcript variants have been found; however, their biological validity has not been determined. [provided by RefSeq
  • Other Designations:
  • CD1E antigen,CD1E antigen, e polypeptide,OTTHUMP00000018910,OTTHUMP00000018913,OTTHUMP00000018914,OTTHUMP00000018915,OTTHUMP00000018916,OTTHUMP00000018920,T-cell surface glycoprotein CD1e,differentiation antigen CD1-alpha-3,leukocyte differentiation antig
  • RSS
  • YouTube
  • Linkedin
  • Facebook