Mouse monoclonal antibody raised against Natural Killer Cell Activation Structures.
Native purified from IL-2-activated cultured NK cells of Wag rats.
ANK61 reactivity is rat strain-independent. The antigen recognized by ANK61 is highly expressed on freshly isolated and cultured rat NK cells. The antibodies also bind to rat alphabeta-TCR T cells and at a low level to rat B cells. Binding to other cell types is unknown. Triggering of the antigen by ANK61 antibodies activates the lytic machinery of rat NK cells, but not of T cells.
The optimal working dilution should be determined by the end user.
In culture supernatant (0.05% sodium azide)
Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.