Mouse monoclonal antibody raised against native NEFH.
Native purified bovine NEFH.
The monoclonal antibody reacts specific with the heavy component of the three subunits of neurofilaments. In immunoblots it reacts with the 200 kD protein. Neurofilaments, the intermediate filaments of neurons, are composed of three polypeptides with a moleculeweight of respecitively, 70, 160 and 200 kD. The three polypeptides can be differentially expressed during neuronal development, or in adult brain tissue. Antibodies directed against the three different neurofilament proteins can be an important aid in studying neurofilament expression pattern and in testing of tumours.
Recommend dilution at 1:10 The optimal working dilution should be determined by the end user.
In tissue culture supernatant (0.09% sodium azide)
Store at 4°C.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.