Ptprc monoclonal antibody, clone EM-05 (APC)
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More Files
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Flow Cytometry
Surface staining of mouse blood lymphocytes with Ptprc monoclonal antibody, clone EM-05 (APC) (Cat # MAB5118).
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Specification
Product Description
Rat monoclonal antibody raised against native Ptprc.
Immunogen
Native purified Ptprc from mouse peripheral blood leukocytes.
Host
Rat
Reactivity
Mouse
Specificity
This antibody reacts with mouse CD45 antigen (Leukocyte Common Antigen), a single chain type I transmembrane protein expressed at high level on cells of hematopoietic origin, except erythrocytes and platelets.
Form
Liquid
Conjugation
APC
Concentration
0.1 mg/mL
Isotype
IgG
Recommend Usage
Flow Cytometry (4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.2% BSA, 0.09% sodium azide)
Storage Instruction
Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Flow Cytometry
Surface staining of mouse blood lymphocytes with Ptprc monoclonal antibody, clone EM-05 (APC) (Cat # MAB5118). -
Gene Info — Ptprc
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Interactome
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Publication Reference
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Involvement of CD45 in DNA fragmentation in apoptosis induced by mitochondrial perturbing agents.
Desharnais P, Dupere-Minier G, Hamelin C, Devine P, Bernier J.
Apoptosis 2008 Feb; 13(2):197.
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Combinations of CD45 isoforms are crucial for immune function and disease.
Dawes R, Petrova S, Liu Z, Wraith D, Beverley PC, Tchilian EZ.
Journal of Immunology 2006 Mar; 176(6):3417.
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CD45-null transgenic mice reveal a positive regulatory role for CD45 in early thymocyte development, in the selection of CD4+CD8+ thymocytes, and B cell maturation.
Byth KF, Conroy LA, Howlett S, Smith AJ, May J, Alexander DR, Holmes N.
The Journal of Experimental Medicine 1996 Apr; 183(4):1707.
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Involvement of CD45 in DNA fragmentation in apoptosis induced by mitochondrial perturbing agents.
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