CD69 monoclonal antibody, clone FN50 (PE)
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Specification
Product Description
Mouse monoclonal antibody raised against native CD69.
Immunogen
Native purified CD69 from human B lymphocytes.
Host
Mouse
Reactivity
Human
Specificity
This antibody recognizes CD69, an lymphocyte early activation marker.
Form
Liquid
Conjugation
PE
Isotype
IgG1
Recommend Usage
Flow Cytometry (20 ul in human blood cells 100 ul in whole blood or 106 cells in a suspension)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.2% BSA, 0.09% sodium azide)
Storage Instruction
Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Flow Cytometry
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Gene Info — CD69
Entrez GeneID
969Gene Name
CD69
Gene Alias
CLEC2C
Gene Description
CD69 molecule
Omim ID
107273Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the calcium dependent lectin superfamily of type II transmembrane receptors. Expression of the encoded protein is induced upon activation of T lymphocytes, and may play a role in proliferation. Furthermore, the protein may act to transmit signals in natural killer cells and platelets. Alternative splicing results in multiple transcript variants
Other Designations
C-type lectin domain family 2, member C|CD69 antigen (p60, early T-cell activation antigen)
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Interactome
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Disease
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Publication Reference
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Expression of CD69 on T-cell subsets in HIV-1 disease.
Pitsios C, Dimitrakopoulou A, Tsalimalma K, Kordossis T, Choremi-Papadopoulou H.
Scandinavian Journal of Clinical and Laboratory Investigation 2009 Jul; 68(3):233.
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CD69 on CD56+ NK cells and response to chemoimmunotherapy in metastatic melanoma.
Konjevic G, Jovic V, Vuletic A, Radulovic S, Jelic S, Spuzic I.
European Journal of Clinical Investigation 2007 Nov; 37(11):887.
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Expression of the activation antigen CD69 predicts functionality of in vitro expanded peripheral blood mononuclear cells (PBMC) from healthy donors and HIV-infected patients.
Nielsen SD, Afzelius P, Ersboll AK, Nielsen JO, Hansen JE.
Clinical and Experimental Immunology 1998 Oct; 114(1):66.
Application：Flow Cyt, Human, PBMCs.
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Expression of CD69 on T-cell subsets in HIV-1 disease.
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