TFRC monoclonal antibody, clone MEM-75 (Biotin)
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Specification
Product Description
Mouse monoclonal antibody raised against native TFRC.
Immunogen
Native purified TFRC from NALM-6 human pre-B cell line.
Host
Mouse
Theoretical MW (kDa)
95
Reactivity
Human
Specificity
This antibody reacts with CD71 antigen (transferrin receptor), a 95 KDa type II homodimeric transmembrane glycoprotein expressed on activated B and T lymphocytes, macrophages and erythroid precursors; it is lost on resting blood leukocytes. This antibody does not block binding of transferrin to the receptor.
Form
Liquid
Conjugation
Biotin
Isotype
IgG1
Recommend Usage
Flow Cytometry (1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (0.09% sodium azide)
Storage Instruction
Store at 4°C. Do not freeze.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Flow Cytometry
Surface staining of NALM-6 (human peripheral blood pre-B cell leukemia cell line) with TFRC monoclonal antibody, clone MEM-75 (Biotin) (Cat # MAB5014); detection by Streptavidin-PE. Total viable cells were used for analysis. -
Gene Info — TFRC
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Interactome
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Pathway
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Disease
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Publication Reference
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Hsa, an adhesin of Streptococcus gordonii DL1, binds to alpha2-3-linked sialic acid on glycophorin A of the erythrocyte membrane.
Yajima A, Urano-Tashiro Y, Shimazu K, Takashima E, Takahashi Y, Konishi K.
Microbiology and Immunology 2008 Feb; 52(2):69.
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Flow cytometric analysis of human bone marrow perfusion cultures: erythroid development and relationship with burst-forming units-erythroid.
Rogers CE, Bradley MS, Palsson BO, Koller MR.
Exp Hematol 1996 Apr; 24(5):597.
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Cell surface antigen expression in human erythroid progenitors: erythroid and megakaryocytic markers.
Nakahata T, Okumura N.
Leukemia & Lymphoma 1994 May; 13(5-6):401.
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Hsa, an adhesin of Streptococcus gordonii DL1, binds to alpha2-3-linked sialic acid on glycophorin A of the erythrocyte membrane.
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