ENG monoclonal antibody, clone 2H6F11
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Specification
Product Description
Mouse monoclonal antibody raised against native ENG.
Immunogen
Human endoglin fusion protein.
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG1
Recommend Usage
Flow Cytometry (20 uL/106 cells)
The optimal working dilution should be determined by the end user.Storage Buffer
In buffer containing 1% BSA, pH 7.2 (0.09% sodium azide).
Storage Instruction
Store in the dark at 4°C. Avoid prolonged exposure to light.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunofluorescence
Flow Cytometry
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Gene Info — ENG
Entrez GeneID
2022Gene Name
ENG
Gene Alias
CD105, END, FLJ41744, HHT1, ORW, ORW1
Gene Description
endoglin
Gene Ontology
HyperlinkGene Summary
This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
CD105 antigen|OTTHUMP00000022221|Osler-Rendu-Weber syndrome 1
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Interactome
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Disease
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