Mouse monoclonal antibody raised against native CD44. The monoclonal antibody is directed against the CD44- antigen, which is mainly expressed on leucocytes and erythrocytes. Very few types of tissue or cells lack CD44. Cells and tissues that lack CD44 include platelets, hepatocytes, certain lymphoid cell lines, cardiac muscle, kidney tubular epithelium, testis and portions of the skin. The CD44 antigen is present on approximately 90% of lymphocytes, monocytes, and granulocytes and in lower amounts on thymocytes, fibroblasts, and erythrocytes.
Protein A/G purification
Flow Cytometry (20 uL/106 cells) The optimal working dilution should be determined by the end user.
In buffer containing 1% BSA, pH 7.2 (0.09% sodium azide).
Store in the dark at 4°C. Avoid prolonged exposure to light.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq
CD44 antigen,CD44 antigen (homing function and Indian blood group system),CDW44 antigen,GP90 lymphocyte homing/adhesion receptor,Hermes antigen,antigen gp90 homing receptor,cell adhesion molecule,cell surface glycoprotein CD44,chondroitin sulfate proteogl