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Last updated: 2017/1/15
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CFB monoclonal antibody, clone KT24

  • Catalog # : MAB4954
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against native CFB
  • Immunogen:
  • Native purified human IL1R1.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Sandwich ELISA (1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Sandwich ELISA
  • Application Image
  • Sandwich ELISA
  • Gene Information
  • Entrez GeneID:
  • 629
  • Gene Name:
  • CFB
  • Gene Alias:
  • BF,BFD,CFAB,FB,FBI12,GBG,H2-Bf,PBF2
  • Gene Description:
  • complement factor B
  • Gene Summary:
  • This gene encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. Polymorphisms in this gene are associated with a reduced risk of age-related macular degeneration. The polyadenylation site of this gene is 421 bp from the 5' end of the gene for complement component 2. [provided by RefSeq
  • Other Designations:
  • B-factor, properdin,C3 proaccelerator,C3 proactivator,C3/C5 convertase,OTTHUMP00000029283,OTTHUMP00000174690,glycine-rich beta-glycoprotein
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