Mouse monoclonal antibody raised against native Synpo.
Native purified Synpo from rat kidney glomeruli.
Bovine, Guinea pig, Human, Mouse, Rat
Recognizes differentiated podocytes (glomerular visceral epithelial cells) in vivo and in vitro (weaker additional reaction with arterial endothelial cells), co-localization with alpha-actinin. Does not react with parietal cells. Reacts with a subset of exclusively telencephalic synapses. Differentiation-dependent expression during postnatal maturation of rat brain. Differentiation-dependent expression in cultured hippocampal neurons. Reacts specifically with synaptopodin, a prolin-rich actin-binding protein with 2 binding sites for actin. Cross-reacts with human, bovine, rat, mouse, guinea pig and gerbil. Does not cross-react with rabbit, frog or chicken.
The optimal working dilution should be determined by the end user.
In buffer containing 0.01% sodium azide
Store at 4°C.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.