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ITGA2 monoclonal antibody, clone Gi9

  • Catalog # : MAB4665
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against native ITGA2.
  • Immunogen:
  • Native purified ITGA2 from isolated human platelets.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • The molecular weight of the recognized antigen is 138/115KDa under non-reducing conditions and 145/126KDa under reduced conditions. Recognizes the VLA2 antigen (alpha 2 beta 1 complex) also called Ia/IIa glycoprotein complex or collagen receptor. This antibody reacts with the molecules carrying the Br(a) as well as the Br(b) alloantigen. It reacts with platelets, megakaryocytes and activated T cells. Does not react with B lymphocytes, T lymphocytes, monocytes, granulocytes and red blood cells. This antibody inhibits the adhesion of platelets to collagen.
  • Form:
  • Lyophilized
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Lyophilized from PBS (1mg/mL BSA)
  • Storage Instruction:
  • Store at 4°C on dry atmosphere.
    After reconstitution with deionized water, store at -20°C or lower.
    Aliquot to avoid repeated freezing and thawing.
  • Publication Reference
  • Applications
  • Flow Cytometry
  • Application Image
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 3673
  • Gene Name:
  • ITGA2
  • Gene Alias:
  • Gene Description:
  • integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
  • Gene Summary:
  • This gene product belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane glycoproteins composed of a distinct alpha chain and a common beta chain. They are found on a wide variety of cell types including, T cells, fibroblasts and platelets. Integrins are involved in cell adhesion and also participate in cell-surface mediated signalling. [provided by RefSeq
  • Other Designations:
  • integrin alpha 2,platelet antigen Br,platelet glycoprotein GPIa,platelet glycoprotein Ia,very late activation protein 2 receptor, alpha-2 subunit
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