Mouse monoclonal antibody raised against native CD36.
Native purified CD36 from human fetal red blood cells.
The molecular weight of the recognized antigen is 90KDa. Recognizes the glycoprotein gp lllb corresponding to the thrombospondin receptor. This antibody agglutinates fetal but not adult erythrocytes. It does not react with lymphocytes and granulocytes. It reacts both with fetal and adult monocytes, megakaryocytes, platelets and reticulocytes. The thrombospondin receptor is a very early marker of erythroid differentiation.
Immunofluorescence (2ug/5x105 cells) Flow Cytometry (2ug/5x105 cells) The optimal working dilution should be determined by the end user.
Lyophilized from PBS (1mg/mL BSA)
Store at 4°C on dry atmosphere. After reconstitution with deionized water, store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
CD36 antigen,CD36 antigen (collagen type I receptor, thrombospondin receptor),PAS-4 protein,cluster determinant 36,fatty acid translocase,glycoprotein IIIb,leukocyte differentiation antigen CD36,platelet glycoprotein IV,scavenger receptor class B, member