FCGR3B monoclonal antibody, clone MEM-154 (FITC)
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Mouse monoclonal antibody raised against native FCGR3B.
Immunogen
Native purified FCGR3B from human granulocytes.
Host
Mouse
Reactivity
Human
Specificity
This antibody reacts with the epitope on CD16 antigen that residing in proximity to FG loop (probably BC or C'E loop). This antibody reacts with CD16+ granulocytes.
Form
Liquid
Conjugation
FITC
Isotype
IgG1
Recommend Usage
Flow Cytometry (20 ul in human blood cells 100 ul in whole blood or 106 cells in a suspension)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.2% BSA, 0.09% sodium azide)
Storage Instruction
Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Flow Cytometry
-
Gene Info — FCGR3B
Entrez GeneID
2215Gene Name
FCGR3B
Gene Alias
CD16, CD16b, FCG3, FCGR3
Gene Description
Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
Omim ID
610665Gene Ontology
HyperlinkGene Summary
low affinity IIIb
Other Designations
Fc fragment of IgG, low affinity IIIb, receptor for (CD16)|Fc-gamma receptor IIIb (CD 16)|low affinity immunoglobulin gamma Fc region receptor III-B
-
Interactome
-
Pathway
-
Disease
-
Publication Reference
-
IgE-mediated activation of NK cells through Fc gamma RIII.
Arase N, Arase H, Hirano S, Yokosuka T, Sakurai D, Saito T.
Journal of Immunology 2003 Mar; 170(6):3054.
-
The binding epitopes of human CD16 (Fc gamma RIII) monoclonal antibodies. Implications for ligand binding.
Tamm A, Schmidt RE.
Journal of Immunology 1996 Aug; 157(4):1576.
Application:Flow Cyt, Human, HEK 294 cells.
-
A triallelic Fc gamma receptor type IIIA polymorphism influences the binding of human IgG by NK cell Fc gamma RIIIa.
de Haas M, Koene HR, Kleijer M, de Vries E, Simsek S, van Tol MJ, Roos D, von dem Borne AE.
The Journal of Immunology 1996 Apr; 156(8):2948.
-
IgE-mediated activation of NK cells through Fc gamma RIII.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com